TY - JOUR
T1 - Investigating the Phytochemicals and Antimicrobial Properties of Three Sedge (Cyperaceae) Species
AU - Adeniyi, T.A. AU - Adeonipekun, P.A. AU - Omotayo, A.E.
JO - International Journal of Tropical Medicine
VL - 8
IS - 4
SP - 92
EP - 98
PY - 2013
DA - 2001/08/19
SN - 1816-3319
DO - ijtmed.2013.92.98
UR - https://makhillpublications.co/view-article.php?doi=ijtmed.2013.92.98
KW - Cyperus esculentus
KW -Cyperus rotundus
KW -Mariscus alternifolius
KW -phytochemicals
KW -antimicrobial properties
KW -plant extracts
KW -sedges
AB - In order to evaluate the medicinal value of notorious sedge
weeds, three species: Cyperus esculentus, Cyperus rotundus and
Mariscus alternifolius were investigated for their phytochemical constituents
and antimicrobial properties. Preliminary qualitative phytochemical constituents
and in vitro antimicrobial activities were evaluated against four fungi
species Aspergillus niger, Aspergillus fumigatus, Penicillium
chrysogenum and Candida albicans and three bacteria species Escherichia
coli, Salmonella typhi and Staphylococcus aureus. Two solvents,
water and ethanol were used to produce the extracts and screened for their antimicrobial
activity. Antimicrobial activity evaluation of extracts against the pathogens
was carried out at 100 mg mL-1 concentration by Disc Diffusion Method
for fungi and Disc Diffusion and Agar Well Diffusion Methods for bacteria. Observed
activities were related to standard antibiotics fulcin (antifungal), tetracycline
(antibacterial) and Ciprofloxacin (antibacterial) which served as controls.
Phytochemically, the plant extracts showed the presence of carbohydrates, flavonoids,
ketose sugars, steroids, reducing sugars and tannins. The ethanolic extract
of C. rotundus exhibited highest activity against A. niger, E.
coli and S. aureus. No extract was active against C. albicans.
From these findings, C. rotundus is a potential source of bioactive compounds
for new drugs upon isolation and purification for treating infections caused
by these pathogens.
ER -