TY - JOUR T1 - Effect of a Polyherbal Formulation (Diarun plus) on Streptozotocin Induced Experimental Diabetes AU - , G. Senthilvel AU - , M. Jegadeesan AU - , Anoop Austin AU - , P. Thirugnanasambantham AU - , E. Mayisvren AU - , M. Balasubramanian AU - , N. Narayanan AU - , S. Viswanathan JO - International Journal of Tropical Medicine VL - 1 IS - 2 SP - 88 EP - 92 PY - 2006 DA - 2001/08/19 SN - 1816-3319 DO - ijtmed.2006.88.92 UR - https://makhillpublications.co/view-article.php?doi=ijtmed.2006.88.92 KW - Diarun plus KW -polyherbal KW -hyperglycemia KW -diabetes mellitus KW -streptozotocin AB - Diarun plus was evaluated for its therapeutic antihyperglycemic activity in streptozotocin-induced diabetes in animal models. It was effective in controlling hyperglycemic status in rats and mice. The drug (500 mg/kg) showed significant antidiabetic property as judged by serum glucose levels. However, it did not significantly influence the levels of serum insulin in both diabetic and normoglycemic rats. This is a promising drug to develop standardized phytomedicine for diabetes mellitus. The findings suggest that it can be considered as a therapeutic agent, wherever elevated glycemic status is observed. ER -