TY  - JOUR
T1  - Kinetics and Tolerance of Salinomycin in Camels
AU - Al-Nazawi, M.H. AU - Homeida, A.M. 
JO  - Research Journal of Pharmacology
VL  - 3
IS  - 3
SP  - 48
EP  - 51
PY  - 2009
DA  - 2001/08/19
SN  - 1815-9362
DO  - rjpharm.2009.48.51
UR  - https://makhillpublications.co/view-article.php?doi=rjpharm.2009.48.51
KW  - Camel
KW  -pharmacokinetics
KW  -tolerance
KW  -salinomycin
KW  -serobiochemical
KW  -peak plasma
AB  - The pharmacokinetics of salinomycin following oral administration of 0.1 μg kg<SUP>-1</SUP> body weight was studied in camels. Peak plasma concentration occurred at 40 min and decline after 2 h to fall below the limit of assay detection at 16 h post-dosing, with terminal half-life of 150 min. Animals given salinomycin at doses of 0.4-0.8 μg kg<SUP>-1</SUP> orally developed neurological signs with some serobiochemical alterations. It is concluded that camels may be one of the most sensitive species to salinomycin toxicity.
ER  -