TY - JOUR T1 - A Comparative Study of Efficacy of Vacuum Assisted Closure Therapy and Conventional Moist Dressings in the Management of Diabetic Ulcers AU - Ravinder, Gudas AU - Kumar, A. AU - Rathod, Ramesh JO - Research Journal of Medical Sciences VL - 19 IS - 1 SP - 677 EP - 680 PY - 2025 DA - 2001/08/19 SN - 1815-9346 DO - makrjms.2025.1.677.680 UR - https://makhillpublications.co/view-article.php?doi=makrjms.2025.1.677.680 KW - Elite handball players KW - handball KW - risk factors KW - prevention KW - athletes AB - Diabetic foot ulcers (DFUs) are a common and severe complication of diabetes mellitus, often leading to amputations and significant morbidity. Negative pressure wound therapy (NPWT) has emerged as an advanced alternative to conventional moist dressings for the management of DFUs. This study aims to compare the efficacy of NPWT with conventional moist dressings in enhancing the healing process of diabetic wounds. A prospective, randomized comparative study was conducted with 112 patients diagnosed with chronic diabetic wounds. Patients were divided into two groups: 56 patients received NPWT (Group 1), while the remaining 56 underwent conventional moist dressing therapy (Group 2). Wound size, depth, and granulation tissue formation were assessed at regular intervals using a Vernier caliper and the Wagner ulcer classification system. Patient satisfaction and the rate of minor and major amputations were also recorded. Statistical analysis was performed using SPSS software. NPWT significantly reduced ulcer size (P = 0.04) and improved granulation tissue formation (80% in NPWT vs. 40% in conventional dressing). Patient satisfaction was notably higher in the NPWT group, with a significant reduction in minor and major amputations. The Wagner score also demonstrated better outcomes in the NPWT group compared to the conventional dressing group. NPWT is a superior treatment modality for diabetic foot ulcers, offering faster healing, reduced ulcer size, enhanced granulation tissue formation, and improved patient satisfaction. It also decreases the likelihood of amputation, making it a preferred choice for diabetic wound management. ER -