TY - JOUR
T1 - Phytochemical, Pharmacognostic, Anti-Radical, Anti-Arthritic and Antibacterial Potential of
the Leaf Extract of Dialium guineense
AU - Zacchaeus S., Ololade AU - Iyadunni A, Anuoluwa AU - Paul, Ishaku
JO - Research Journal of Applied Sciences
VL - 16
IS - 5
SP - 192
EP - 203
PY - 2021
DA - 2001/08/19
SN - 1815-932x
DO - rjasci.2021.192.203
UR - https://makhillpublications.co/view-article.php?doi=rjasci.2021.192.203
KW - secondary metabolite
KW -leaf extract
KW -Dialium guineense
KW -pharmacological activities
KW -evaluates
AB - This research evaluates the extract of the leaf
of Dialium guineense for its phytochemical and
pharmacognostic potential. GC-MS, UV-Visible
Spectrophotometer and other established biochemical
methods assays were used for the study. GC-MS analysis
showed the presence of 37 phytochemicals. The main
component was: 4-O-methylmannose (49.0%). The
β-carotene, lycopene, total carotenoid, chlorophyll a, b,
total chlorophyll, TPC, TFC, TTC, TAA values were
0.20 mgg1, 0.10 mgg1, 12.68 mgg1, 4.40 mgg1,
4.70 mgg1, 7.80 mgg1, 2,668.17±0.01 μgmg1,
17.80±0.00 μgmg1, 152.65±0.01 μgmg1, 43.75±0.04,
μgmg1, respectively while Galvinoxyl and DPPH
antioxidant IC50 were 125.0 and 6.0 μgmL1, respectively.
The TAC value was 279.49±0.01 μgmg1. The highest
anti-arthritic value was 96.00%. The extract inhibited the
growth of all the screener bacteria. These results showed
that the leafcan be used in the treatment of various human
and animals related aliment or diseases and more
importantly in formulation food additives and
preservative.
ER -