TY  - JOUR
T1  - Some Langmuir and Freundlich Parameters of Adsorption Studies of Chlorpheniramine Maleate
AU - , A.C. Tella AU - , S.O. Owalude 
JO  - Research Journal of Applied Sciences
VL  - 2
IS  - 8
SP  - 875
EP  - 878
PY  - 2007
DA  - 2001/08/19
SN  - 1815-932x
DO  - rjasci.2007.875.878
UR  - https://makhillpublications.co/view-article.php?doi=rjasci.2007.875.878
KW  - In-vitro adsorption
KW  -Chlorpheniramine Maleate
KW  -adsorbents Langmuir and Freundlich parameters
KW  -adsorption capacities
AB  - The <I>in-vitro</I> adsorption of chlorpheniramine maleate on activated charcoal, magnesium trisilicate, talc powder and magnesium carbonate have been studied at 37<SUP>o</SUP>C and  pH = 5.0 using the Batch method. Both the Langmuir and Freundlich parameters were determined for each adsorbent and their values used in determination of adsorption capacities of each. The results show that the adsorption capacities increased in the order Activated carbon > Magnesium trisilicate > magnesium stearate > Talc power. This in-vitro study indicates that some chlorpheniramine maleate may be lost when it is administered concomitantly with pharmaceutical adsorbents.
ER  -