TY - JOUR T1 - Prevalence of Acinetobacter baumannii in Iran: Systematic Literature Review AU - Ghazvini, Kiarash AU - Kaffash, Afsaneh AU - Ashena, Habib JO - Research Journal of Biological Sciences VL - 15 IS - 4 SP - 94 EP - 101 PY - 2020 DA - 2001/08/19 SN - 1815-8846 DO - rjbsci.2020.94.101 UR - https://makhillpublications.co/view-article.php?doi=rjbsci.2020.94.101 KW - Acinetobacter baumannii KW -drug resistance KW -nosocomial infections KW -frequency KW -dissemination AB - Acinetobacter species, especially Acinetobacter baumannii (A. baumannii) that show resistance to a wide range of antibiotics is thought to be the most important cause of nosocomial infections among patients hospitalized in different wards. In this study, we aimed to systematically review the literatures and study the frequency and resistance of A. baumannii in Iran. A systematic literature search was performed in the PubMed, Scopus and Google scholar using the following key terms “Acinetobacter baumannii”, “frequency” and “Iran” in the title, abstract and keywords of articles to study the dissemination, resistance and susceptibility of A. baumannii to some conventional antibiotics in Iran. After collecting the relevant articles, the data of desired were extracted and analyzed based on the purpose of this study. Of total 384 articles found, 364 were excluded in several steps of article selection and only 20 relevant documents with 1911 studied patients were included. The results of this study showed that prevalence of multidrug resistance A. baumannii is very high in Iran. Moreover, it was shown that polymyxin B, colistin, tigecylcin and minocycline were most effective antibiotics against A. baumannii infections. Respiratory tract and burn samples were the most common place for isolation of bacterial strains. The results of this review showed that A. baumannii is widely disseminated in Iran and it shows high resistance to most antibiotics. In addition, A. baumannii is responsible for nosocomial infection in patients, especially those who are hospitalized at ICU and burn unit. ER -