TY - JOUR
T1 - Prevalence of Acinetobacter baumannii in Iran: Systematic Literature Review
AU - Ghazvini, Kiarash AU - Kaffash, Afsaneh AU - Ashena, Habib
JO - Research Journal of Biological Sciences
VL - 15
IS - 4
SP - 94
EP - 101
PY - 2020
DA - 2001/08/19
SN - 1815-8846
DO - rjbsci.2020.94.101
UR - https://makhillpublications.co/view-article.php?doi=rjbsci.2020.94.101
KW - Acinetobacter baumannii
KW -drug resistance
KW -nosocomial infections
KW -frequency
KW -dissemination
AB - Acinetobacter species, especially Acinetobacter
baumannii (A. baumannii) that show resistance to a wide
range of antibiotics is thought to be the most important
cause of nosocomial infections among patients
hospitalized in different wards. In this study, we aimed to
systematically review the literatures and study the
frequency and resistance of A. baumannii in Iran. A
systematic literature search was performed in the
PubMed, Scopus and Google scholar using the following
key terms “Acinetobacter baumannii”, “frequency” and
“Iran” in the title, abstract and keywords of articles to
study the dissemination, resistance and susceptibility
of A. baumannii to some conventional antibiotics in Iran.
After collecting the relevant articles, the data of desired
were extracted and analyzed based on the purpose of this
study. Of total 384 articles found, 364 were excluded in
several steps of article selection and only 20 relevant
documents with 1911 studied patients were included. The
results of this study showed that prevalence of multidrug
resistance A. baumannii is very high in Iran. Moreover, it
was shown that polymyxin B, colistin, tigecylcin and
minocycline were most effective antibiotics against
A. baumannii infections. Respiratory tract and burn
samples were the most common place for isolation of
bacterial strains. The results of this review showed
that A. baumannii is widely disseminated in Iran and it
shows high resistance to most antibiotics. In addition,
A. baumannii is responsible for nosocomial infection in
patients, especially those who are hospitalized at ICU and
burn unit.
ER -