TY - JOUR T1 - Potential Effects of Agricultural Fungicide (Mancozeb) on Fish Clarias batrachus AU - Singh, Ajay AU - Srivastava, Pallavi JO - Research Journal of Biological Sciences VL - 9 IS - 4 SP - 129 EP - 134 PY - 2014 DA - 2001/08/19 SN - 1815-8846 DO - rjbsci.2014.129.134 UR - https://makhillpublications.co/view-article.php?doi=rjbsci.2014.129.134 KW - Dithiocarbamates KW -fingerlings KW -Mancozeb KW -Clarias batrachus KW -India AB - The subclasses of carbamate pesticides, i.e., dithiocarbamates are being used in pest control programs because of their low toxicity. However, it has announced effects on aquatic organisms, especially on fishes. Therefore in the present study, the effects of exposure of fungicide on Clarias batrachus on different tissues have examined. The LC values (LC50) estimated on different life stages of fish which were dose, as well as time dependent. LC50 differences has found in both adult and fingerlings, indicated that Mancozeb was more sensitive for fingerlings than adults. The bioassay study has performed after 24 and 72 h. Marked changes have observed in biochemical and enzymatic pathways in a single exposure, 40% of LC50 (10.86 mg L¯1 ) due to secondary metabolites of fungicide Mancozeb. The changes in the level of these parameters may because of cellular damage and impairment of enzymes in oxidative metabolisms which effect on the release of enzymes. Therefore, the findings of present investigation show that Mancozeb has potential to damage biochemicals and enzymatic pathways in fish. Therefore, it is suggested that appropriate toxicological risk assessment should be made in those areas where Mancozeb is proposed to be used in pest control activities. ER -