TY  - JOUR
T1  - Correlation of Mast Cell Numbers and Different Periodontal Diseases
AU - Vahabi, Surena AU - Rezazadeh, Fahime AU - Movaghar, Sepideh Ebrahimi AU - Nazemisalman, Bahare 
JO  - Research Journal of Biological Sciences
VL  - 5
IS  - 4
SP  - 340
EP  - 344
PY  - 2010
DA  - 2001/08/19
SN  - 1815-8846
DO  - rjbsci.2010.340.344
UR  - https://makhillpublications.co/view-article.php?doi=rjbsci.2010.340.344
KW  - Mast cell
KW  -periodontal disease
KW  -inflammation
KW  -chronic
KW  -aggressive
KW  -Iran
AB  - Mast cells play an important role in allergic reactions, host defense, local homeostasis, inflammation and angiogenesis. The objective of this study was to evaluate the relationship between mast cell numbers and different types of periodontal diseases. Gingival specimens were taken from 20 moderate to advanced chronic periodontal and 19 moderate to advanced aggressive periodontal sites as case groups and 18 healthy/gingivitis sites as control group in routine periodontal flaps and crown lengthening procedures. All the specimens were stained by toluidine-blue for mast cells counting and hematoxylin-eosin to assess inflammation. Inflammatory and mast cells in 5 micron sections were assessed by two observers 3 times, utilizing light microscope at 100 and 400x magnification. Anova and T tests with an alpha error level <5% were used to analyze data. Mast cells numbers were higher in chronic versus aggressive periodontitis and healthy/gingivitis (p = 0.000). The aggressive periodontitis did not have more numbers of mast cells as compared to healthy/gingivitis (p>0.05). There were no relationship between mast cell numbers and degree of inflammation in 3 groups. The present study indicates more mast cell numbers presence in the chronic periodontitis sites than other sites. The results of this study suggest more studies to evaluate dynamic aspects of host defense in conjunct with other aspects of immune system, simultaneously.
ER  -