TY - JOUR T1 - Antioxidant Activity and Chemical Constituents of Pupalia lappacea (L.) Juss AU - , A. Aladedunye Felix AU - , A. Okorie Domingo JO - Research Journal of Biological Sciences VL - 3 IS - 7 SP - 783 EP - 785 PY - 2008 DA - 2001/08/19 SN - 1815-8846 DO - rjbsci.2008.783.785 UR - https://makhillpublications.co/view-article.php?doi=rjbsci.2008.783.785 KW - Pupalia lappacea (L.) Juss. (Amaranthaceae) KW -ecdysteroid KW -20-hydroxyecdysone KW -antioxidant activity KW -saropeptate AB - Phytochemical analysis of foliage of Pupalia lappacea (L.) Juss (Amaranthaceae) afforded 8 compounds, namely; 1-docosanol, stearic acid, stigmasterol, -sitosterol, N-benzoyl-L-phenylalaninol acetate, -sitosterol-3-O- -D-glucopyranoside, stigmasterol-3-O- -D-glucopyranoside and 20-hydroxyecdysone. The ecdysteroid, 20-hydroxyecdysone, constitutes nearly 0.3% of the dry weight and 13% of the dichloromethane extracts of the plant, making Pupalia lappacea a probable commercial source for this important ecdysteroid. Both the hexane and dichloromethane extracts showed significant antioxidant activity with the dichloromethane exhibiting an IC50 comparable to that of BHT, a synthetic antioxidant. All the isolated compounds are reported for the first time in the genus. ER -