TY - JOUR
T1 - Evaluation the Functional Status of the Liver in Elite Jordanian Athletes Compared with Healthy Controls
AU - Mansi, Kamal AU - Aburjai, Talal AU - Ermili, Ziad AU - Ata, Ahmad Bani AU - M. Hawamdeh, Ziad
JO - International Journal of Molecular Medicine and Advance Sciences
VL - 9
IS - 1
SP - 1
EP - 4
PY - 2013
DA - 2001/08/19
SN - 1813-176x
DO - ijmmas.2013.1.4
UR - https://makhillpublications.co/view-article.php?doi=ijmmas.2013.1.4
KW - ALP
KW -AST
KW -ALT
KW -liver
KW -athletes
KW -glucose
AB - Owing to considerable physical, endocrinological and metabolic
adaptations, the analysis of biochemical data in elite and top-class athletes
requires caution. With the aim to identify metabolic and biochemical adaptations
to particular lifestyle conditions such as regular and strenuous physical exercise
researchers measured the concentration of liver enzymes, bilirubin and serum
albumin in Jordanian top athletes. A healthy liver is essential to optimum performance
by athletes. Good liver function is required to burn fat, build muscle and provide
energy. Sixty Jordanian first class athletes (34 males and 26 females, mean
age 19.8±2 years with training experience of at least 5 years and with
a minimal training load of 18 training hours per week participated in competitive
different sports chosen in the study. Group of healthy male and female (control
group), matched for age and gender was also included (n = 60). No subject revealed
evidences of cardiovascular disease, diabetes (fasting glucose <7 mmol L-1)
or hypertension (blood pressure <130/80 mm Hg) when tested by specialized
physicians. The levels of AST, ALT and ALP for evaluation the liver functions
in athletes in different groups were measured 15-18 h rest and 12 h fasting
using commercial analytical kits. The results showed a significant differences
(p<0.5) were observed between experimental and control group for AST (34.18±13.23
and 26.19±7.42 U L-1, respectively) for ALT (28.47±8.43
and 17.38±10.83 U L-1, respectively) and for ALP (127.85±67.54
and 83.49±19.45 U L-1, respectively). The concentration of
serum albumin was decreased in athletes but the difference did not reach statistical
significance (controls: 4.82± 0.37 g L-1; athletes: 4.72±0.27
g L-1). No effect of endurance exercise on serum bilirubin in healthy
athletes. Researchers concluded that the most abnormalities observed on routine
biochemical screening in elite Jordanian athletes are of no clinical significance.
ER -