TY - JOUR T1 - Mechanism of Action, Toxicity and Nutritional Significance of Heat-Labile Antinutritional Factors in Some Legumes: A Review AU - , D.B. Oke JO - Journal of Food Technology VL - 5 IS - 4 SP - 286 EP - 289 PY - 2007 DA - 2001/08/19 SN - 1684-8462 DO - jftech.2007.286.289 UR - https://makhillpublications.co/view-article.php?doi=jftech.2007.286.289 KW - Mechanism of action KW -toxicity and nutritional significance KW -antinutritional factors KW -Nigeria AB - Legumes which are widely consumed all over the world have constituent that depress their utilization. Some of these constituents called antinutritional factor, trypsin inhibitor and haemagglutinin, are heat-labile. Trypsin inhibitor inhibits growth by interfering with the digestion of protein in the intestine of animals thereby causing hypertrophy of the pancreas. Unless legumes are heated before consumption, methionine would be slowly liberated by the proteolytic enzymes and its absorption delayed. Because iectins are capable of agglutinating red blood cells, intake of or improperly cooked legumes is deleterious. Phytohaemagglutinins are known to exert a non-selective adverse effect on the absorption of nutrients form the intestinal tract rather than a direct effect on the digestive process. ER -