TY - JOUR T1 - Status of Oxidative DNA Damage in Serum and Saliva of Dairy Cows During Lactation and Dry Period AU - Ellah, Mahmoud R. Abd AU - Okada, Keiji AU - Shimamura, Shinsuke AU - Kobayashi, Saori AU - Sato, Reeko AU - Yasuda, Jun JO - Journal of Animal and Veterinary Advances VL - 13 IS - 9 SP - 577 EP - 581 PY - 2014 DA - 2001/08/19 SN - 1680-5593 DO - javaa.2014.577.581 UR - https://makhillpublications.co/view-article.php?doi=javaa.2014.577.581 KW - Cows KW -8-OHdG KW -total antioxidant capacity KW -lactation KW -dry period AB - The present study, researchers evaluated for the first time serum and salivary 8-Hydroxy-2'-deoxyguanosine (8-OHdG) and salivary Total Antioxidant Capacity (TAC) during different stages of lactation and also during the dry period in dairy cows. Cows at dairy farms that belong to Morioka City (Iwate, Japan) were classified into five groups according to the month of lactation starting from postpartum till the dry period. Oxidative DNA damage marker (8-OHdG) and TAC were measured in saliva and serum samples using commercial ELISA kits. The results revealed that salivary 8-OHdG levels were higher (p<0.01) than its corresponding serum levels during both lactation and dry period. Serum levels of TAC were significantly higher (p<0.01) than their salivary levels during lactation and dry period. It could be concluded that oxidative DNA damage was prominent during the dry period. Cows at the dry period have the highest serum level of 8-OHdG and the lowest salivary level of TAC when compared to lactating cows. ER -