TY - JOUR
T1 - Characterization of Antimicrobial Resistance and Enterotoxin Genes in Methicillin-Resistant
Staphylococcus aureus Isolated from Mastitis Milk and Food Poisoning
Cases
AU - Li, Jinnian AU - Huang, Ying AU - Yao, Lu AU - Li, Lin AU - Liu, Xueqin AU - Huang, Anning AU - Zhang, Tingting AU - Wang, Wenping
JO - Journal of Animal and Veterinary Advances
VL - 13
IS - 7
SP - 423
EP - 429
PY - 2014
DA - 2001/08/19
SN - 1680-5593
DO - javaa.2014.423.429
UR - https://makhillpublications.co/view-article.php?doi=javaa.2014.423.429
KW - enterotoxin gene
KW -antimicrobial resistance
KW -S. aureus
KW -Methicillin-resistant
KW -raw milk
KW -food poisoning
AB - Enterotoxigenic Staphylococcus aureus is a main cause
of Staphylococcal Food Poisoning (SFP). Here, researchers characterized the
antimicrobial resistance, distribution and expression of enterotoxin genes of
41 Methicillin-Resistant S. aureus (MRSA) isolated from bovine mastitis
milk and SFP cases. Apart from three SFP-acquired isolates which could produce
extended-spectrum β-lactamases, all the others carried mecA gene
and expressed the penicillin-binding protein 2a. The 92.7% of MRSA isolates
tested showed twenty two multi-drug resistant patterns among which SFP-acquired
isolates had higher resistant rate and the MIC50/90 values of cefotaxime,
amikacin, azithromycin, ciprofloxacin and gentamicin than those of milk-acquired
isolates. The 95.1% of MRSA isolates carried at least one Staphylococcal Enterotoxins
(SEs) gene and could produce the corresponding classical SEs, the differences
in the prevalence of enterotoxigenic MRSA observed between milk-acquired and
SFP-acquired isolates were not statistically significant. Six SEs genotypes
were found, among which the genotypes sea-seg-sei-seln-selm and sea-seb-sec-seg-sei-seln-selm
predominated, respectively in milk-acquired and SFP-acquired isolates.
ER -