TY - JOUR T1 - Antimicrobial Peptides Characteristics and their Application in Domestic Animals AU - Hu, Yao-Dong AU - Lu, Lu AU - Huang, Xiu AU - Zhang, Long AU - Lan, Dan AU - Li, Di-yan AU - Liu, Yi-Ping JO - Journal of Animal and Veterinary Advances VL - 13 IS - 21 SP - 1185 EP - 1193 PY - 2014 DA - 2001/08/19 SN - 1680-5593 DO - javaa.2014.1185.1193 UR - https://makhillpublications.co/view-article.php?doi=javaa.2014.1185.1193 KW - Antimicrobial peptides KW -application KW -domestic animals KW -regulation KW -AMPs AB - Antimicrobial Peptides (AMPs) are principal defense system for most organisms. Multiple AMPs have been characterized as widespread conserved component and showing a wide spectrum of effectiveness to the various microorganisms. Despite of the antibacterial activity, AMPs have also been found can serving as other immune effects including modulation of inflammatory responses, promotion of wound healing and chemotactic activity. AMP drugs have been actively developed and lightly applied in animal production. In this review, we will brief the activities and functional mechanisms of AMPs as well as a warning of the potential resistance to AMPs used directly. Moreover, we will focus on a potential application strategy, by regulating the expression of AMPs which may delay or avoid the resistance to AMPs. Finally, the status and obstacles of AMPs used in domestic animals will be described. ER -