TY - JOUR
T1 - Associations of Single SNP and Q-PCR of Leptin Gene with Growth Traits in Chinese Luxi Cattle
AU - Yang, Dongying
JO - Journal of Animal and Veterinary Advances
VL - 12
IS - 6
SP - 791
EP - 794
PY - 2013
DA - 2001/08/19
SN - 1680-5593
DO - javaa.2013.791.794
UR - https://makhillpublications.co/view-article.php?doi=javaa.2013.791.794
KW - Chinese Luxi cattle
KW -leptin gene
KW -PCR-SSCP
KW -Q-PCR
KW -polymorphism
KW -growth traits
AB - Leptin is encoded by obsese gene is an adipocyte-secreted
cytokine. The main function of it is to regulate the balance of energy through
the signal transduction pathway and it has a strong relationship with the function
of reproduction, organism immune. PCR-SSCP and SYBGREEN Q-PCR was used to analyze
the polymorphism of leptin gene and expression difference in 139 samples
of Luxi (LX) cattle breeds. The association of variations of leptin gene
with growth traits was analyzed. Some indexes of the individuals with genotype
BB were higher than that with genotype AA and AB in LX breed such as the indexes
of body length, heart length, body weight, hucklebone width, body height. Leptin
express high in the white adipose tissue but there is little expression in the
organ or the tissue such as heart, liver, kidney, spleen, lung and muscle. These
results may be applied to Marker-Assisted Selection (MAS) of Chinese LX cattle
breeds improving the economic traits of cattle.
ER -