TY - JOUR
T1 - Biological Activities of Kinetin on Animals
AU - Yang, Dongying
JO - Journal of Animal and Veterinary Advances
VL - 12
IS - 6
SP - 671
EP - 675
PY - 2013
DA - 2001/08/19
SN - 1680-5593
DO - javaa.2013.671.675
UR - https://makhillpublications.co/view-article.php?doi=javaa.2013.671.675
KW - Kinetin
KW -biological activity
KW -antiaging
KW -buds
KW -plant cells
AB - As a cytokinin growth factor kinetin (N6-furfuryladenine)
with several biological effects observed for human cells and fruit flies. It
was named kinetin because of its ability to induce cell division. The mechanism
of kinetin synthesis in DNA is thought to be via the production of furfural,
an oxidative damage product of DNA deoxyribose and it is quenched by the adenine
base converting it into N6-furfuryladenine. Since 1994, kinetin has
been thoroughly tested for its powerful antiaging effects in human skin cells
and other systems. At present, kinetin is one of the most widely used components
in numerous skin care cosmetics and cosmeceuticals. Kinetin which was isolated
50 years ago for the first time as a plant hormone as well as other cytokinins
isopentenyladenine, zeatin and benzylaminopurine induce callus (clusters of
dedifferentiated plant cells) to redifferentiate into adventitious buds. Because
of some similarities in the biological phenotypes of cancer and callus cells,
cytokinins and especially kinetin, affect the differentiation of human cells
through a common signal transduction system. Therefore, cytokinins found their
way to use in molecular medicine.
ER -