TY  - JOUR
T1  - Changes in Biochemical, Hematological and Cytokine in Endurance Horses with 
  Metabolic Crises
AU - Adamu, Lawan AU - Mohd Adzahan, Noraniza AU - Abdullah, Rasedee AU - Ahmad, Bashir 
JO  - Journal of Animal and Veterinary Advances
VL  - 11
IS  - 18
SP  - 3431
EP  - 3436
PY  - 2012
DA  - 2001/08/19
SN  - 1680-5593
DO  - javaa.2012.3431.3436
UR  - https://makhillpublications.co/view-article.php?doi=javaa.2012.3431.3436
KW  - Nigeria
KW  -Endurance horses
KW  -metabolic crises
KW  -biochemical
KW  -hematological
KW  -cytokine
AB  - Metabolic crises are the convoluted and injurious physiological changes observed in eliminated endurance horses during endurance races. Therefore, this study aims to evaluate the changes in biochemical hematological and cytokine in endurance horses with metabolic crises. The 32 endurance horses between the ages of 6-20 years and weighing between 350-450 kg were examined to be clinically healthy pre-ride. The 16 horses were eliminated post-race as a result of metabolic crises. Blood sample were collected at pre and post ride. The blood samples were analyzed for biochemical, hematological and cytokine. The parameters were assessed using one-way analysis of variance. There were significant increases in RBC, Hb and PCV (p<0.0001). There were significant increases in MCV (p<0.0104) and a significant decrease in MCHC (p<0.0039). There were significant increases in WBC segmented neutrophil and monocytes (p<0.0001). Band neutrophil (p<0.0003) and lymphocytes (p<0.0043). There was a significant increase in IL-6 (p<0.0004). Significant decreases were observed in sodium and potassium (p<0.0001) and chloride (p<0.0004) while significant increases were also assessed in total protein, urea, lactate and creatine kinase (p<0.0001) AST (p<0.0049) glucose (p<0.0207) plasma protein and uric acid (p<0.0014). In conclusion metabolic crises are the major causes of eliminations and poor performance in endurance horses. Thus, this study aims to evaluate the biochemical, hematological and cytokine as indicative of metabolic crises and poor performance in endurance horses.
ER  -