TY  - JOUR
T1  - Protective Effects of Crude Polysaccharide from <I>Gynostemma pentaphyllum </I>on Swimming Exercise-Induced Oxidative Stress in Rat
AU - Li, Changjun AU - Wu, Xiaolan AU - Lou, Xiaojuan AU - Wu, Yajun AU - Li, Ang AU - Wang, Haiyan 
JO  - Journal of Animal and Veterinary Advances
VL  - 11
IS  - 10
SP  - 1627
EP  - 1632
PY  - 2012
DA  - 2001/08/19
SN  - 1680-5593
DO  - javaa.2012.1627.1632
UR  - https://makhillpublications.co/view-article.php?doi=javaa.2012.1627.1632
KW  - Crude polysaccharide from Gynostemma pentaphyllum
KW  -oxidative stress
KW  -swimming exercise
KW  -rat
KW  -SOD
KW  -China
AB  - The present study examined the effects of crude Polysaccharide from <I>Gynostemma pentaphyllum</I> (PGP) against oxidative stress induced by swimming exercise. Male rats were administered PGP (50, 100, 200 and 400 mg kg<SUP>-1</SUP>) by gavage every day. After 30 days, swimming exercise of rat was performed in acrylic plastic pool. The results showed that PGP treatment prolonged exhaustive swimming time and improved liver glycogen reserve which suggested that PGP treatment influenced the performance of exhaustive exercise and improved exercise tolerance. Moreover, PGP treatment can promote increases in the activities of Super Oxide Dismutase (SOD), Catalase (CAT) and Glutathione Peroxidase (GPH-Px) and reduce lipid per-oxidation which suggest that PGP treatment was beneficial in enhancing the antioxidant status and inhibiting oxidative stress induced by exhaustive exercise.
ER  -