TY  - JOUR
T1  - Decreased Levels of Ghrelin in Brucellosis
AU - Kilic, Nermin AU - Kilic, Suleyman Sirri 
JO  - Journal of Animal and Veterinary Advances
VL  - 11
IS  - 10
SP  - 1552
EP  - 1554
PY  - 2012
DA  - 2001/08/19
SN  - 1680-5593
DO  - javaa.2012.1552.1554
UR  - https://makhillpublications.co/view-article.php?doi=javaa.2012.1552.1554
KW  - Brucellosis
KW  -headach
KW  -sweats
KW  -chills
KW  -radio-immunoassay
KW  -blood
AB  - Ghrelin is a growth-hormone releasing lipopeptide that was shown to regulate of lipid and carbohydrate metabolism and appetite. Brucellosis characterized by fever, headache, night sweats, extreme tiredness, chills and weight loss and anorexia. This research aimed to investigate the changes of ghrelin concentrations in blood of brucellosis patients 19 brucellosis patients and 16 healthy subjects with similar ages were randomly selected as control group. Serum levels of acylated ghrelin were evaluated on blood samples of the participants by Radio-Immunoassay Methods. The results showed acylated ghrelin was significantly changed in patients with brucellosis (8.9&plusmn;2 pg mL<SUP>-1</SUP>) compared with controls (39&plusmn;15.5 pg mL<SUP>-1</SUP>). There is no data showing ghrelin in Brucellosis in literature so far. The first evaluated results showed that appetite decrease in Brucellosis might be due to circulating level of ghrelin decrement.
ER  -