TY  - JOUR
T1  - <I>MSTN</I> Gene Polymorphism and its Relationships with Growth Performance in Ma Shen Porcine
AU - , Hongbing Han AU - Guan, Xueming AU - , Yanfang Liu AU - , Fenglian Bian AU - , Wenjing Zhu 
JO  - Journal of Animal and Veterinary Advances
VL  - 11
IS  - 8
SP  - 1173
EP  - 1176
PY  - 2012
DA  - 2001/08/19
SN  - 1680-5593
DO  - javaa.2012.1173.1176
UR  - https://makhillpublications.co/view-article.php?doi=javaa.2012.1173.1176
KW  - Ma Shen swine
KW  -5`-regulator region of the Myostatin gene
KW  -mutation
KW  -growth traits
KW  -genotype
AB  - Myostatin gene (<I>MSTN</I>) is a negative regulator of myogenesis which is related to total lean meat yield. A total of 339 individuals of three breeds were used to analyzed polymorphisms by the Polymerase Chain Reacton Single-Strand Conformation Polymorphism (PCR-SSCP) method in the 5'-promoter region of MSTN. This study analyzed the relationship of mutation with the growth traits including Weight at Birth (WB) and Weaning Weight (WW) in Ma Shen swine breeds. Two alleles (A and B) and three genotypes (AA, AB and BB) were identified in MSTN promoter region of Ma Shen swine. The result showed that WB of individuals with genotype BB was significant higher than that with genotype AA and AB (p&lt;0.05). No statistically significant differences were observed in WW (p&gt;0.05) among MSTN variation.
ER  -