TY - JOUR T1 - Plasmid Mediated Streptomycin and Sulfonamide Resistance in Haemophilus parasuis AU - , Qigai He AU - Chen, Pin AU - , Yingyu Liu AU - , Yang Wang AU - , Wentao Li AU - , Dingren Bi JO - Journal of Animal and Veterinary Advances VL - 11 IS - 8 SP - 1106 EP - 1109 PY - 2012 DA - 2001/08/19 SN - 1680-5593 DO - javaa.2012.1106.1109 UR - https://makhillpublications.co/view-article.php?doi=javaa.2012.1106.1109 KW - Haemophilus parasuis KW -streptomycin KW -sulfonamide KW -plasmid KW -pig KW -China AB - Streptomycin and sulfonamide resistance in Haemophilus parasuis is an emerging phenomenon that has not yet been characterized from a molecular perspective. The aim of the present research was to determine the molecular mechanism of Haemophilus parasuis resistant to streptomycin and sulfonamide. One high level streptomycin and sulfonamide-resistant isolate from China was submitted for MIC determination and plasmid extract, then sequencing and annotation. One plasmid extracted from the bacteria strain, designated pHPS-A67 (4.2 kb), contain fifteen open reading frames including streptomycin resistance gene StrA, sulfonamide resistance gene Sul 2 and mobilization protein genes Mob A, Mob B and Mob C. This is believed to be the first report of native Haemophilus parasuis contains plasmid which mediated streptomycin and sulfonamide resistance in this microorganism. ER -