TY - JOUR T1 - Residue Depletion of Florfenicol and its Metabolite Florfenicol Amine in Eggs AU - Xie, Kaizhou AU - Guo, Huisheng AU - Jia, Longfei AU - Huang, Yuping AU - Xie, Xing AU - Yao, Yilin AU - Xu, Dong AU - Chen, Xuesheng AU - Dai, Guojun AU - Zhang, Xiaojie AU - Sun, Yingying AU - Wang, Jinyu AU - Liu, Zongping JO - Journal of Animal and Veterinary Advances VL - 11 IS - 7 SP - 1012 EP - 1017 PY - 2012 DA - 2001/08/19 SN - 1680-5593 DO - javaa.2012.1012.1017 UR - https://makhillpublications.co/view-article.php?doi=javaa.2012.1012.1017 KW - Florfenicol KW -florfenicol amine KW -residue depletion KW -eggs KW -yolk KW -yolk AB - Eggs of laying hens were used to study residue depletion of Florfenicol (FF) and its metabolite Florfenicol Amine (FFA) after oral dose (25.0, 50.0 and 100.0 mg kg-1 body weight), once daily for 5 days. The residues were determined by High Performance Liquid Chromatography with Fluorescence Detection (HPLC-FLD). The maximum concentration of FF was all detected at 1 day in the albumen, yolk and whole eggs; the maximum concentration of FFA was detected at 1 day in the albumen and whole eggs, at 3 days in the yolk after cessation of medication. After oral administration of 100.0 mg kg-1, concentrations of FF and FFA were all below the LODs (1.5 μg kg-1 for FF and 0.5 μg kg-1 for FFA) at 7 days for the albumen, 11 days for yolk and 10 days for whole egg after cessation of medication. ER -