TY - JOUR T1 - Discover of a Novel SNP Highly Associated with Chicken Blue Egg AU - Wang, A.R. AU - Li, J.Y. AU - Deng, X.M. AU - Wang, X.T. AU - Wang, Z.P. AU - Liu, R.F. JO - Journal of Animal and Veterinary Advances VL - 10 IS - 1 SP - 92 EP - 95 PY - 2011 DA - 2001/08/19 SN - 1680-5593 DO - javaa.2011.92.95 UR - https://makhillpublications.co/view-article.php?doi=javaa.2011.92.95 KW - Chicken KW -association KW -linkage KW -chromosome KW -blue egg KW -SNP AB - Blue egg is caused by a dominant mutation, Oocyan (O) which is previous located on short arm of chicken chromosome 1 but precise genetic mechanism underlying blue egg is still unknown so far. In this study, we found a SNP (g.67419892-67419904del13) significantly associated with blue egg using 126 browned-shelled chickens and 202 blue-shelled chickens. The allelic and genotypic frequencies of g.67419892-67419904del13 are significantly higher in blue-shelled chickens (92.5 and 87.1%) compared with brown-shelled chickens (10.7 and 8.7%, p<0.0001). Moreover, the genetic distance between O and g.67419892-67419904del13 is estimated to be over 2 cM (LOD = 13.51) using 149 F2 offspring from mating between blue-shelled males and brown-shelled females. Apparently, the marker is useful for the cloning of O and marker aid selection of blue-shelled chicken breed. ER -