TY  - JOUR
T1  - Association of 5-Flanking Region of <I>Pit-1</I> Gene Polymorphisms with Growth Traits in Goose
AU - Chen, Guo-Hong AU - Zhang, Yang AU - Li, Xiu AU - Huang, Zheng-Yang AU - Xu, Qi AU - Qiao, Na AU - Zhao, Rong-Xue AU - Zhao, Wen-Ming 
JO  - Journal of Animal and Veterinary Advances
VL  - 10
IS  - 5
SP  - 651
EP  - 655
PY  - 2011
DA  - 2001/08/19
SN  - 1680-5593
DO  - javaa.2011.651.655
UR  - https://makhillpublications.co/view-article.php?doi=javaa.2011.651.655
KW  - genetic marker
KW  -Goose
KW  -polymorphism
KW  -Single Nucleotide Polymorphism (SNP)
KW  -Pit-1
AB  - The aim of the present study was to detect Single Nucleotide Polymorphism (SNP) in some areas of <I>Pit-1</I> gene of goose to find genetic marker influencing on growth and carcass trait. The Single Nucleotide Polymorphism (SNP) of <I> Pit-1 </I> gene promoter was investigated in Wanxi geese. The primers for promoter in <I>Pit-1 </I> gene were designed according to the <I> Pit-1 </I>gene promoter of goose and the SNPs were detected by PCR-SSCP method. The results showed that only C-930T was detected for SNP and two genotypes (CC and TT) were found, respectively. The analysis of least square on genotypes and groups showed that there were significant differences (p&lt;0.01) on body weight of different weeks in different groups and genotypes, however, there were no differences (p&gt;0.05) on body weight of different weeks in genotype-group interaction effect, then, comparison of bodyweight in different groups show that the average body weight of wanxi white goose was the largest, the average body weight of taihu goose was larger than zi goose. Variance analysis on genotype suggested that the average body weight of CC genotype and TT genotype had significant differences (p&lt;0.05) in 6, 8 weeks and had extremely significant differences (p&lt;0.05) in 10 weeks. This study indicated that the polymorphic site could be a genetic marker for growth trait.
ER  -