TY - JOUR T1 - Isolating, Mapping and Spatio-Temporal Distribution Analysis of Five Ubiquitin-Specific Protease Genes in Porcine AU - Tang, X.M. AU - Tan, Y.S. AU - Zhu, L.L. AU - Wu, X. AU - Zhang, X.B. JO - Journal of Animal and Veterinary Advances VL - 10 IS - 4 SP - 524 EP - 527 PY - 2011 DA - 2001/08/19 SN - 1680-5593 DO - javaa.2011.524.527 UR - https://makhillpublications.co/view-article.php?doi=javaa.2011.524.527 KW - porcine KW -China KW -big muscle tissue KW -mapping KW -Ubiquitin-specific protease KW -expreesion AB - The Ubiquitin-proteasome system is an essential mechanism for protein degradation in eukaryotes and ubiquitin-specific proteases are key effectors of the Ubiquitin-proteasome system. About 5 porcine USP genes (14, 16, 38, 44 and 54) were isolated and shared high sequence similarity with their human homologues genes. Then, the tissue expression pattern of 5 porcine USP genes were analysed by RT-PCR in 2 breeds (a domestic breed and a foreign breed) and the results showed that USP 14, 16, 38 and 54 gene expression were higher in muscle tissue. In addition, researchers mapped the 5 porcine genes and all chromosomes assignments were consistent with known chromosomal homologies between human and pig. All results provided a basis for further function study of these 5 USP genes. ER -