TY - JOUR T1 - Microencapsulation of Lactobacillus brevis and Preliminary Evaluation of Their Therapeutic Effect on the Diarrhea of Neonatal Calf AU - Zhao, Xianjun AU - Jin, Yaping AU - Wang, Aihua AU - Liu, Hongming AU - Qi, Xuefeng JO - Journal of Animal and Veterinary Advances VL - 10 IS - 2 SP - 151 EP - 156 PY - 2011 DA - 2001/08/19 SN - 1680-5593 DO - javaa.2011.151.156 UR - https://makhillpublications.co/view-article.php?doi=javaa.2011.151.156 KW - diarrhea of neonatal calf KW -Microencapsulation KW -Lactobacillus brevis KW -administration KW -ERIC-PCR KW -evaluate AB - Microcapsules of Lactobacillus brevis were prepared using spray drying technique and the resistance of the microencapsulated form of this microorganism to drying at high temperature and simulated gastrointestinal conditions were evaluated. The therapeutic effect of these microcapsules on the diarrhea of neonatal calf was also evaluated using ERIC-PCR. The results showed that the completely release of the encapsulated bacteria took place after 60 min in contact with simulated intestinal conditions. Microencapsulated bacteria were resistant at least for 90 min to simulated gastric juice (pH 1.2) or simulated intestinal juice (pH 7.2) and microencapsulated form of the microorganisms was more resistant to drying at 85°C than free form. ERIC-PCR profiles of diarrhea calves treated with probiotic capsules were similar to that of control health calves at 3 days post administration suggesting that administration of these probiotic capsules may have strong positive effect on the treatment of neonatal calf diarrhea. ER -