TY  - JOUR
T1  - Detection of Some Biochemical and Lipid Peroxidation Parameters in <I>Dirofilaria immitis</I> Infected Dogs
AU - Aslan, Oznur AU - Yildirim, Alparslan AU - Kanbur, Murat AU - Altinordu, Sule 
JO  - Journal of Animal and Veterinary Advances
VL  - 9
IS  - 5
SP  - 954
EP  - 957
PY  - 2010
DA  - 2001/08/19
SN  - 1680-5593
DO  - javaa.2010.954.957
UR  - https://makhillpublications.co/view-article.php?doi=javaa.2010.954.957
KW  - Dogs
KW  -lipid peroxidation
KW  -plasma
KW  -Dirofilaria immitis
KW  -ivermectin
KW  -Turkey
AB  - This research has compared the levels of some biochemical and lipid peroxidation parameters between the <I>Dirofilaria immitis</I> infected and ivermectin treated dogs. The dogs of the experimental group were treated with 0.05 mg kg<SUP>-1</SUP> ivermectin and blood samples were collected on the 7th day after treatment. The blood samples were analyzed for microfilariae (mf) concentration and the plasma samples were analyzed for MDA and NO levels, serum ALP, ALT, AST, CHOL, GGT, total protein and triglyceride levels on day 0 and 7. The results of this study showed that the MDA and NO levels of the dogs naturally infected with <I>D. immitis</I> were higher than those of the control group. It was also demonstrated that ivermectin treatment is effective on <I>D. immitis</I> microfilariae. Consequently, heartworm disease causes lipid peroxidation in dogs but ivermectin treatment possesses no regulatory effects on serum biochemical parameters, except for NO and AST.
ER  -