TY  - JOUR
T1  - Investigation on Efficacy of a Commercial Vaccine for Treatment of Leptospirosis in Cattle
AU - Kaygusuz, Sedat AU - Gazyagci, Serkal AU - Yildirim, Murat 
JO  - Journal of Animal and Veterinary Advances
VL  - 9
IS  - 10
SP  - 1531
EP  - 1533
PY  - 2010
DA  - 2001/08/19
SN  - 1680-5593
DO  - javaa.2010.1531.1533
UR  - https://makhillpublications.co/view-article.php?doi=javaa.2010.1531.1533
KW  - treatment
KW  -prognosis
KW  -leptospirosis
KW  -Lepto Shield 5®
KW  -Cattle
KW  -vaccination
AB  - The aim of this study was to determinate leptospirosis in cattle and to investigate efficacy of a commercial vaccine in treatment of leptospirosis. Upon observing leptosipirosis specific clinical signs including haematuria and mucosal icterus in 2 heifers and mouse fleshes on the surface of the water reserve of the farm, the clinicians tentatively diagnosed the diseased heifers as leptosiprosis. In addition, 9 heifers had general clinical signs including fever, apathy and tachypnea. Blood samples were collected from 41 heifers kept in the farm, including those exhibiting specific and non-specific clinical signs. All clinically diseased heifers were seropositive for leptosirosis confirmed by Microagglutination Test (MAT). The antibody titers were 1/100 or above in 11 out of 41 heifers (26.8%). All 41 heifers were vaccinated with a specific commercial vaccine (Lepto Shield 5<SUP>&reg;</SUP>) developed against leptospirosis. At the forth day of vaccination, one of the diseased heifers died of acute leptospirosis while the others clinically recovered 8 days after vaccination and none of the seropositive heifers showed any clinical signs of the disease. No side effects were observed within a month following vaccination. The results of the present study suggest that Lepto Shield 5<SUP>&reg; </SUP>is effective not only for protection but also for treatment of leptospirosis in cattle.
ER  -