TY - JOUR T1 - Peptidergic Innervation of the Mammary Gland in the Pregnant, Lactating and Non-lactating Periods of Guinea Pig AU - , Mine Yaman AU - , Berrin Gencer Tarakci AU - , Ali Bayrakdar JO - Journal of Animal and Veterinary Advances VL - 7 IS - 6 SP - 712 EP - 716 PY - 2008 DA - 2001/08/19 SN - 1680-5593 DO - javaa.2008.712.716 UR - https://makhillpublications.co/view-article.php?doi=javaa.2008.712.716 KW - Nerve fibres KW -mammary gland KW -guinea pig KW -immunohistochemistry AB - The presence and distribution of some biologically active substances in nerve fibres supplying the mammary gland in the pregnant, lactating and non-lactating guinea pig were studied using immunohistochemical methods. The substances studied included: Calcitonon Gene Related Peptide (CGRP), substance P (SP), Vasoactive Intestinal Polypeptide (VIP), Galanin (GAL), Cholecystokinin (CCK) and neurotensin. Immunoreactive nerve fbres were associated with blood vessel, lactiferous ducts and alveoli. CGRP, SP, VIP, GAL, CCK and neurotensin immunoreactive fibres appeared to be much more numerous in the mammary gland of pregnant and lactating guinea pigs when compared to non-lactating guinea pigs. The results demonstrate a rich distribution of different types of nerve fibres in structures of mammary gland related to milk ejection. These nerve fibres may be involved in the local control of milk ejection. ER -