TY  - JOUR
T1  - Effects of Monensin, Virginiamycin and Sodium Bicarbonate on Ruminal Fermentation and Acid-Base Status in Sheep
AU - , E. Candanosa AU - , A. Villa-Godoy AU - , D.A. Castillo AU - , G.D. Mendoza 
JO  - Journal of Animal and Veterinary Advances
VL  - 7
IS  - 2
SP  - 184
EP  - 189
PY  - 2008
DA  - 2001/08/19
SN  - 1680-5593
DO  - javaa.2008.184.189
UR  - https://makhillpublications.co/view-article.php?doi=javaa.2008.184.189
KW  - Monensin
KW  -virginiamycin
KW  -sodium bicarbonate
KW  -sheep
KW  -fermentation
AB  - Four ruminally canulated sheep (55±10 kg initial BW) were used in a 4×4 Latin square design to evaluate the effects of monensin, virginiamycin and sodium bicarbonate on ruminal fermentation and acid-base balance  in  sheep  fed  a  diet  with  60%  concentrate  (DM  basis).  Treatments  included  control,  monensin (25 mg d <SUP>1</SUP>), virginamycin (15 mg d <SUP>1</SUP>) and sodium bicarbonate (10 g d <SUP>1</SUP>)  intraruminally. Each period included 14 d of adaptation and 4 d of sample collection. Ruminal fluid samples were collected at 0, 2, 4, 6, 8 and 10 h after the additive dose. Blood samples were collected at 0 and 6 h to determine pH, HCO<SUB>3</SUB>, pCO<SUB>2</SUB>, base excess, electrolytes (Na<SUP>+</SUP>, K<SUP>+</SUP>, Cl<SUP>-</SUP>) and other metabolites (glucose, urea, L-lactate, NEFA). Intake was increased (p&lt;0.05) with virginiamycin in comparison with sodium bicarbonate. Addition of sodium bicarbonate reduced significantly (p&lt;0.05) DM intake. Sheep with monensin showed increased proportion of propionate at time of feeding, while virginiamycin lowered percentage of acetate in rumen liquor sampled 10 hours after feeding. Protozoa counts were not affected by the additives. Monensin, virginiamycin or sodium bicarbonate did not affected acid base status in sheep.
ER  -