TY - JOUR T1 - Effect of Rice-Based Solution on Intestinal Water Movement and Motility: Studies in a Model of Prostaglandins-Induced Secretory Diarrhea and the Myoenteric Plexus Preparation AU - , Bitri lotfi AU - , Ben Saad Moncef JO - Journal of Animal and Veterinary Advances VL - 4 IS - 8 SP - 730 EP - 733 PY - 2005 DA - 2001/08/19 SN - 1680-5593 DO - javaa.2005.730.733 UR - https://makhillpublications.co/view-article.php?doi=javaa.2005.730.733 KW - Rice KW -diarrhea KW -water movement KW -myorelaxation AB - Rice-based solution was studied for its antidiarrheal potencies. Two experiments were conducted to test its antisecretory and antimotility properties on intestine. In experiment 1, studies in a model of prostaglandins-induced secretory diarrhea in rat jejunum and colon have been performed to verify the antisecretory effect of a rice-based solution. When administered intraluminally, rice water reduced dose dependently the prostaglandin E1-induced net fluid secretion in both intestinal segments. In experiment 2, rice water was tested for its potency as inhibitor of electrically-evoked contractions of the myenteric plexus-longitudinal muscle preparation of guinea-pig small intestine. Aqueous rice extract exerts a myorelaxant effect, it decreases twitch heights of the intestinal strip by acting either on the mucosal or the serosal side. This effect seems to be mediated by an intramural modulatory influence on smooth muscle excitability. ER -