@article{MAKHILLIJTM202116420022,
    title = {Physicochemical Properties and Biological Activities of Common Mullein (<i>Verbascum thapsus
L</i>.) Root, Leaf and Fruit Oils},
    journal = {International Journal of Tropical Medicine},
    volume = {16},
    number = {4},
    pages = {47-52},
    year = {2021},
    issn = {1816-3319},
    doi = {ijtmed.2021.47.52},
    url = {https://makhillpublications.co/view-article.php?issn=1816-3319&doi=ijtmed.2021.47.52},
    author = {Zekeria,Sewnet,Mulugeta and},
    keywords = {zone of inhibition,oil extract,Minimum Inhibitory Concentration (MIC),factorial design,DPPH},
    abstract = {<i>Verbascum thapsus L</i>. is one of the most
common medicinal plant. The purpose of this study was
to examine physicochemical properties, antioxidant and
antimicrobial activities of oil extracted from common
mullein leaves, roots and fruits. The oil extraction was
done in Soxhelt apparatus using hexane as a solvent. The
result of physicochemical properties of <i>V. thapsus</i> fruit,
leaf and root oils presented significantly the highest oil
yield (17.75%) was recorded for the fruit oil extract. Acid
value (acid number) (2.53) and free fatty acid (FFA)
(1.27) value were significantly highest for root oil.
Specific gravity (0.92) and peroxide values (2.20) were
highest for leaf oil. Significantly the highest antioxidant
activities with respect to DPPH (37.35&plusmn;0.64) was
recorded for root oil. The strongest antibacterial activity
with maximum zone of inhibition (14.50 mm), minimum
inhibitory concentration (MIC, 0.19 &#956;L/mL) and
corresponding minimum bactericidal concentration
(MBC, 0.25 &#956;L/mL) was recorded for root oil extract
against <i>Staphylococcus aureus</i> while the strongest
antifungal activity with maximum zone of inhibition
(16.50 mm), MIC (0.09 &#956;L/mL) and MFC (0.18 &#956;L/mL)
were recorded for fruit oil against <i>Aspergillus niger</i>.
Hence, suggesting possible exploitation of these plants for
their antimicrobial active principles for the development
of novel herbal-based antimicrobials.}
    }