@article{MAKHILLIJTM202116220018,
    title = {Bacteriology and Antimicrobial Profile of Urinary Tract Infections in Patients with Human
Immunodeficiency Virus in a Teaching Hospital},
    journal = {International Journal of Tropical Medicine},
    volume = {16},
    number = {2},
    pages = {24-29},
    year = {2021},
    issn = {1816-3319},
    doi = {ijtmed.2021.24.29},
    url = {https://makhillpublications.co/view-article.php?issn=1816-3319&doi=ijtmed.2021.24.29},
    author = {Ifeyinwa,Samuel,Martin,Uchenna,Chinwe and},
    keywords = {Antimicrobials,Bacteriology,ESBLs,HIV,patients,profile,resistance,UTI,treatment},
    abstract = {There has been a rising incidence of treatment
failures of Urinary Tract Infection (UTI) in patients with
Human Immunodeficiency Virus infection (HIV). This
study was carried out to determine the bacteriology of
urinary tract infections in patientswith HIV infections in
University of Nigeria Teaching Hospital, Enugu. The
study was a cross sectional study, involving 300 adult
HIV positive patients, matched for age and sex with
apparently healthy HIV negative subjects as control.
Mid-stream urine samples from both groups were cultured
on MacConkey, blood agar plates and incubated
aerobically at 37°C. Antimicrobial susceptibility testing
was done with agar diffusion method and interpreted
according to CSLI guidelines. Extended spectrum
beta-lactamases production was confirmed phenotypically
using double disc synergy test. The mean age of the
subjects was 22.0±3 years. There was a preponderance of
females 76.0%. (p = 0.493). The prevalence of UTI in the
study group was 5.7% as against 2.7% in the control
group. The most predominant bacteria isolated from study
group were <i>Escherichia coli</i> (55.0%) with the least being
<i>Staphyloccocus saprophyticus</i> (5.0%). In the control
group only <i>Escherichia coli</i> (62.5%) and <i>Klebsiella
pneumoniae</i> (37.5%) were isolated (r = 0.973, p = 0.005).
Most of the organisms isolated were resistant to the
commonly used antibiotics. The 20.0% of the <i>Klebsiella
pneumoniae</i> and 14.0% of <i>Escherichia coli</i> isolated were
ESBL producing. UTI has a higher prevalence among
HIV patients. Most of the organisms isolated were
resistant to the commonly used antibiotics. Routine urine
culture should be done for each patient for appropriate
and judicious antibiotic therapy.}
    }