@article{MAKHILLIJTM20061219687, title = {Effect of a Polyherbal Formulation (Diarun plus) on Streptozotocin Induced Experimental Diabetes}, journal = {International Journal of Tropical Medicine}, volume = {1}, number = {2}, pages = {88-92}, year = {2006}, issn = {1816-3319}, doi = {ijtmed.2006.88.92}, url = {https://makhillpublications.co/view-article.php?issn=1816-3319&doi=ijtmed.2006.88.92}, author = {G. Senthilvel,M. Jegadeesan,Anoop Austin,P. Thirugnanasambantham,E. Mayisvren,M. Balasubramanian,N. Narayanan and}, keywords = {Diarun plus,polyherbal,hyperglycemia,diabetes mellitus,streptozotocin}, abstract = {Diarun plus was evaluated for its therapeutic antihyperglycemic activity in streptozotocin-induced diabetes in animal models. It was effective in controlling hyperglycemic status in rats and mice. The drug (500 mg/kg) showed significant antidiabetic property as judged by serum glucose levels. However, it did not significantly influence the levels of serum insulin in both diabetic and normoglycemic rats. This is a promising drug to develop standardized phytomedicine for diabetes mellitus. The findings suggest that it can be considered as a therapeutic agent, wherever elevated glycemic status is observed.} }