@article{MAKHILLRJMS2024181031675, title = {Association Between Androgenetic Alopecia and Coronary Artery Disease in Men a Prospective Case Study}, journal = {Research Journal of Medical Sciences}, volume = {18}, number = {10}, pages = {616-620}, year = {2024}, issn = {1815-9346}, doi = {makrjms.2024.10.616.620}, url = {https://makhillpublications.co/view-article.php?issn=1815-9346&doi=makrjms.2024.10.616.620}, author = {S.,A.J.S.,Azeem and}, keywords = {Androgenetic alopecia, coronary artery disease, dyslipidemia, hypertension, cardiovascular risk factors, young males}, abstract = {
Androgenetic alopecia (AGA) is a common form of hair loss predominantly affecting males and is linked to genetic and hormonal factors. Emerging evidence suggests that AGA may be associated with systemic health conditions, particularly coronary artery disease (CAD). CAD remains a major cause of morbidity and mortality worldwide and there is growing interest in understanding the potential relationship between AGA and CAD, which may share common risk factors such as dyslipidemia, endothelial dysfunction and insulin resistance. This study aimed to evaluate the association between AGA and CAD in young men, particularly focusing on the prevalence and severity of AGA and its correlation with cardiovascular risk factors, including dyslipidemia, hypertension and smoking. A hospital‐based case‐control study was conducted in South India, involving 150 young male participants aged 18‐45 years. The participants were divided into two groups: 75 CAD patients and 75 age‐matched controls without CAD. The severity of AGA was assessed using the Hamilton‐Norwood scale and cardiovascular risk factors were evaluated through clinical examination and biochemical parameters, including lipid profiles and fasting blood glucose levels. Multivariate logistic regression was performed to identify predictors of CAD. Severe AGA was significantly more prevalent in the CAD group (36%) compared to the control group (10.7%), with moderate and mild AGA being more common in the controls. Severe AGA was also strongly associated with higher levels of dyslipidemia, hypertension and smoking. Multivariate analysis revealed that severe AGA was an independent predictor of CAD (adjusted OR: 3.8, p<0.001). The study suggests a significant association between AGA and CAD in young males, with more severe AGA correlating with higher cardiovascular risk. These findings highlight the potential of AGA as a marker for increased cardiovascular risk, supporting early screening and preventive strategies for individuals with severe AGA.
} }