@article{MAKHILLRJBS20116411224,
title = {Parathyroid Hormone and Calcitonin Regulating Calcium Levels},
journal = {Research Journal of Biological Sciences},
volume = {6},
number = {4},
pages = {183-186},
year = {2011},
issn = {1815-8846},
doi = {rjbsci.2011.183.186},
url = {https://makhillpublications.co/view-article.php?issn=1815-8846&doi=rjbsci.2011.183.186},
author = {Renald and},
keywords = {Calcium,parathyroid hormone,calcitonin,bone,vitamin D and phosphate,Malta},
abstract = {Maintaining normal calcium levels within the body (8.5-10
mg dL-1) requires the action of two hormones in particular: Parathyroid
Hormone (PTH) and calcitonin (http://www.bloodbook.com/ranges.html).
In lower calcium levels, PTH is released and works in such a way as to increase
the calcium back to the normal range. Calcitonin acts exactly in the inverse
way by targeting osteoclasts and osteoblasts. A somewhat constant amount of
calcium is lost from the body through fecal excretion. In the gut, absorption
and secretion of calcium and phosphate occurs, depending on the free ionized
calcium in the extracellular fluid. The amount of calcium in the extracellular
fluid also influences excretion of calcium in the renal system. The largest
pool of calcium is found in bone which is essential in calcium homeostasis.
This is because through bone remodelling, calcium may be taken up from the extracellular
fluid or given up to the extracellular fluid depending on the presence of hormones
in a process known as osteolytic osteolysis. The processes mentioned before
are mediated through PTH, calcitonin and 1,25-dihydroxycholecalciferol.}
}