@article{MAKHILLRJBS20083810688, title = {Maxillary Bone Necrosis Following the Use of Bisphosphonates in Patients with Cancer: Management and Case Series}, journal = {Research Journal of Biological Sciences}, volume = {3}, number = {8}, pages = {925-929}, year = {2008}, issn = {1815-8846}, doi = {rjbsci.2008.925.929}, url = {https://makhillpublications.co/view-article.php?issn=1815-8846&doi=rjbsci.2008.925.929}, author = {Silvia Tortorici,Francesco Burruano,Luigi Caradonna,Maria Lidia Buzzanca and}, keywords = {Bisphosphonates,bone necrosis,avascular necrosis of the jaw,cancer,case series}, abstract = {Bisphosphonates are bone-turnover modulating drugs used to treat various diseases such as certain cancers, bone metastasis, bone- and calcium-related disorders, Paget`s disease, osteoporosis and osteopenia. Recently, several preliminary reports have reported the insurgence of osteonecrosis of the mandible and/or maxilla, associated with intravenously administered bisphosphonates. This case series describes the effects of bisphosphonates used in the treatment of certain cancers on oral bone tissues.} }