@article{MAKHILLIJMMAS2005128478,
    title = {Proinflammatory HIV-1 Pathogenesis and Precarcinogenesis},
    journal = {International Journal of Molecular Medicine and Advance Sciences},
    volume = {1},
    number = {2},
    pages = {105-111},
    year = {2005},
    issn = {1813-176x},
    doi = {ijmmas.2005.105.111},
    url = {https://makhillpublications.co/view-article.php?issn=1813-176x&doi=ijmmas.2005.105.111},
    author = {Lawrence M. Agius},
    keywords = {HIV-I,precarcinogenesis,systemic process},
    abstract = {HIV-1 infection assumes the features of a systemic process affecting cellular cycling events and of inflammatory and neoplastic amplification. It would indeed appear that HIV-1 induces pathways of progression that are specifically transforming in terms of such amplification and self-amplification of cellular and microenvironmental events. The central nervous system in particular would constitute a manifestation of organ integrity that expresses the consequences of amplified transformation of pathobiologic lesions. Neoplasia of the lymphoreticular system would represent a characterization of the nature of such events as further projected by the HIV-1 infection evolving as AIDS dementia and Primary Lymphoma of the CNS and as Progressive Multifocal Leukoencephalopathy or opportunistic infection in general.}
    }