@article{MAKHILLJAVA20131274098,
title = {Early Tool for Prediction of Trypanosoma evansi Infections Related
to Seroprotein Changes of Dromedary in Tunisia},
journal = {Journal of Animal and Veterinary Advances},
volume = {12},
number = {7},
pages = {807-812},
year = {2013},
issn = {1680-5593},
doi = {javaa.2013.807.812},
url = {https://makhillpublications.co/view-article.php?issn=1680-5593&doi=javaa.2013.807.812},
author = {Ramzi Boubaker,Mohamed Fethi,Imen and},
keywords = {Dromedary,trypanosomiasis,electrophoresis,indirect immunoflurorescence,Tunisia},
abstract = {Trypanosomiasis is a haemoprotozoan disease which affects
both human and all species of domesticated mammal, especially Trypanosoma
evansi in dromedaries. In the present study, early tool for prediction of
Trypanosoma evansi infections related to seroprotein changes of dromedary
in Tunisia was studied. Animals were distributed into 3 groups on the basis
of their status related to trypanosomiasis by indirect immunoflurorescence-test:
Healthy animals with negative serology for T. evansi infection, seropositive
animals without clinical signs (apparently healthy) and seropositive diseased
animals. Quantifiable changes in the electropherogram were apparent in dromedaries
infected by trypanosomiasis with a significant hyperprotidemia and an increase
of the gamma globulins fraction in seropositive animals with or without clinical
signs (p<0.05). Moreover, seropositive camels that are not suffering from
majors zoonotic bacterial diseases can cause immunoglobulin secretion. The results
from this study showed that there was specific pattern in serum protein and
electrophorerogram that could be used to distinguish infected with or without
symptoms of T. evansi infection from uninfected animals. It appears that
serum protein electrophoresis can be used by clinicians to predict trypanosomiasis
with great ease in outbreak of T. evansi infection in combination with
serological, clinical and laboratory findings of this disease.}
}