@article{MAKHILLJAVA201211213819, title = {Phenotypic Detection and Drug Resistance Analysis of Extended-Spectrum β-Lactamases among Escherichia coli Isolates from Diseased Duck}, journal = {Journal of Animal and Veterinary Advances}, volume = {11}, number = {21}, pages = {3870-3875}, year = {2012}, issn = {1680-5593}, doi = {javaa.2012.3870.3875}, url = {https://makhillpublications.co/view-article.php?issn=1680-5593&doi=javaa.2012.3870.3875}, author = {Gong-Zheng,Hua,Shan-Mei,Yu-Shan,Bao-Guang and}, keywords = {Duck,Escherichia coli,Extended-Spectrum Beta-Lactamases (ESBLs),phenotype,antibiotics susceptibility}, abstract = {Thirty two Escherichia coli isolates recovered from diseased ducks diagnosed with colibacillosis in China between 2010 and 2011 were characterized for detection of Extended-Spectrum β-Lactamases (ESBLs) by phenotypic screening and confirmatory test provided by the Clinical Laboratory Standards Institute and antimicrobial susceptibility profiles via agar disk diffusion and a broth doubling dilution method. Results showed 7 of the 32 E. coli isolates analyzed (21.87%) were found to be ESBL producers. The resistant rates of ESBL producers were >28.6% against third generation cephalosporins and semisynthetic penicillins and as high as 100% against amoxicillin, ampicillin and ceftiofur. All 32 isolates were sensitive to imipenem, meropenem and cefepime and the susceptible rates of all 32 isolates to β-lactam antibiotics in combination with enzyme inhibitors were higher than those of β-lactam antibiotics alone. Therefore, ESBL-producing isolates had multi-drug resistance and enzyme inhibitors can partially solve the drug resistance problem.} }