@article{MAKHILLJAVA20111042620, title = {Isolating, Mapping and Spatio-Temporal Distribution Analysis of Five Ubiquitin-Specific Protease Genes in Porcine}, journal = {Journal of Animal and Veterinary Advances}, volume = {10}, number = {4}, pages = {524-527}, year = {2011}, issn = {1680-5593}, doi = {javaa.2011.524.527}, url = {https://makhillpublications.co/view-article.php?issn=1680-5593&doi=javaa.2011.524.527}, author = {X.M.,Y.S.,L.L.,X. and}, keywords = {porcine,China,big muscle tissue,mapping,Ubiquitin-specific protease,expreesion}, abstract = {The Ubiquitin-proteasome system is an essential mechanism for protein degradation in eukaryotes and ubiquitin-specific proteases are key effectors of the Ubiquitin-proteasome system. About 5 porcine USP genes (14, 16, 38, 44 and 54) were isolated and shared high sequence similarity with their human homologues genes. Then, the tissue expression pattern of 5 porcine USP genes were analysed by RT-PCR in 2 breeds (a domestic breed and a foreign breed) and the results showed that USP 14, 16, 38 and 54 gene expression were higher in muscle tissue. In addition, researchers mapped the 5 porcine genes and all chromosomes assignments were consistent with known chromosomal homologies between human and pig. All results provided a basis for further function study of these 5 USP genes.} }