@article{MAKHILLJAVA201110193000,
    title = {Possible Association of Single Nucleotide Polymorphism in <I>Titin</I> Gene with Growth-Related Trait in Japanese Black Beef Cattle},
    journal = {Journal of Animal and Veterinary Advances},
    volume = {10},
    number = {19},
    pages = {2603-2606},
    year = {2011},
    issn = {1680-5593},
    doi = {javaa.2011.2603.2606},
    url = {https://makhillpublications.co/view-article.php?issn=1680-5593&doi=javaa.2011.2603.2606},
    author = {Hiroshi,Fumiki,Takahisa,Seiki,Shin,Youichi,Mitsuo and},
    keywords = {beef cattle,Association,growth-related trait,Japanese black breed,single nucleotide polymorphism,TTN},
    abstract = {Growth performance as well as marbling is the main breeding objectives in Japanese Black cattle, the major beef breed in Japan. The researchers have recently reported that a Single Nucleotide Polymorphism (SNP), referred to as g.231054C&gt;T in promoter region of the <I>Titin</I> (<I>TTN</I>) gene was associated with marbling in Japanese Black beef cattle with the T allele being associated with a high level of marbling. The TTN is known to be involved in myofibrillogenesis and has been previously shown to be located within genomic region of a quantitative trait locus for rib eye area. Thus, the TTN was considered as a positional functional candidate for the gene responsible for growth performance. In this study, the researchers analyzed the effect of the TTN g.231054C&gt;T SNP genotypes on the growth-related carcass traits in Japanese Black beef cattle. The SNP was marginally associated with rib eye area in two experiments using 101 sires (p = 0.067) and 820 paternal half-sib progeny steers from 3 sires homozygous for C allele at the g.231054C&gt;T (p = 0.090) in Japanese Black beef cattle. These findings suggest possible effect of the g.231054C&gt;T on the growth-related trait in Japanese Black beef cattle. The TTN SNP polymorphism may be useful for effective marker-assisted selection to increase the beef productivity in Japanese Black beef cattle.}
    }