@article{MAKHILLJAVA201110152919,
    title = {Effects of Chinese Herbal Medicine Additives on Antioxidant Status, Serum Biochemical Parameters and Digestive Enzymatic Activities in Weaned Piglets},
    journal = {Journal of Animal and Veterinary Advances},
    volume = {10},
    number = {15},
    pages = {2004-2009},
    year = {2011},
    issn = {1680-5593},
    doi = {javaa.2011.2004.2009},
    url = {https://makhillpublications.co/view-article.php?issn=1680-5593&doi=javaa.2011.2004.2009},
    author = {Z.J.,L.,C.H.,Y.Y. and},
    keywords = {digesive enzymatic activities,serum biochemical parameters,Chinese herbal medicine additive,China,antioxidant status,Weaned piglets},
    abstract = {The study investigated the effects of Chinese Herbal Medicine Additives (CHMD) supplemented diets on weaned piglets antioxidant status, serum biochemical parameters, digesive enzymatic activities in a 3 weeks trial. Total of 144 crossbred (Duroc x Landrace x Yorkshire) weaning piglets (BW = 5.86&plusmn;0.24 kg) from 18 L with an age of 21 days were selected and divided randomly into 4 groups balanced for sex, weight and litter origin. In each group, the piglets were divided randomly into 3 pens (replicates, 12 pigs per pen), a corn-soybean meal-expanded soybean basal diet without antibiotics or probiotics was used as control and the other 3 groups were fed the control diet supplemented with the CHMD at rations of 0.5, 1 and 1.5% (wt/wt). After completion of the feeding experiment, 3 piglets from each treatment were randomly selected to determine the antioxidant status, serum biochemical parameters, digesive enzymatic activities. In the 3 weeks trial, the data showed that the 1% CHMD group had higher protease activity in stomach digesta than the control and 0.5% CHMD group (p&lt;0.01) than 1.5% CHMD group (p&lt;0.05). The 1.5% CHMD group showed similar significant difference in protease activities of piglets compared with the control group (p&lt;0.05). The 1% CHMD group had higher lipase activity than the control group in the stomach and jejunum digesta (p&lt;0.01) in the duodenum and ileum digesta (p&lt;0.05) and than the 0.5% CHMD group in the stomach and jejunum digesta (p&lt;0.05). The 1% CHMD group had higher amylase activity than the control group in the jejunum digesta (p&lt;0.01) in the duodenum and ileum digesta (p&lt;0.05) and than the 0.5% CHMD group and 1.5% CHMD group in the jejunum digesta (p&lt;0.05). The 1.5% CHMD group had higher amylase activity than the control group in the ileum digesta (p&lt;0.05). The 1% CHMD group had higher T-AOC and CAT activities than the control group and 0.5% CHMD group (p&lt;0.01), than the 1.5% CHMD group (p&lt;0.05). The 1.5% CHMD group had higher T-AOC and CAT activities than the control group (p&lt;0.05). The 1% CHMD group had higher GSH-PX and SOD activities than the control group (p&lt;0.05). The 1% CHMD group (p&lt;0.01) and the 1.5% CHMD group (p&lt;0.05) had lower MDA content than the control group. Compared with the control group, dietary supplementation of 1% CHMD reduced the serum BUN (p&lt;0.05) and increased the total serum protein (p&lt;0.05), reduced the serum triglyceride and total cholesterol contents (p&lt;0.01). The results show that the CHMD used in this study as a dietary additive could enhance the antioxidant status, serum biochemical parameters, digesive enzymatic activities in weaned piglets, additionaly imply that the dose of 1% CHMD supplement is the most ideal concentration to achieve the most beneficial effects.}
    }