@article{MAKHILLJAVA20109102211,
title = {Growth of Staphylococcus aureus, Candida albicans, Escherichia coli and Pseudomonas aeruginosa in Propofol, Thiopental and a 1:1 Propofol-Thiopental Mixture},
journal = {Journal of Animal and Veterinary Advances},
volume = {9},
number = {10},
pages = {1432-1435},
year = {2010},
issn = {1680-5593},
doi = {javaa.2010.1432.1435},
url = {https://makhillpublications.co/view-article.php?issn=1680-5593&doi=javaa.2010.1432.1435},
author = {Nihal Y.,Suna,Cuneyt,Hulya and},
keywords = {thiopental, mixture,propofol,Intravenous anesthetics,bacteria,growth rate},
abstract = {Extrinsic contamination of propofol is thought to be a source of postoperative sepsis. Researchers studied growth of Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli and Candida albicans in propofol, thiopental and in a 1:1 propofol-thiopental mixture. All microorganisms were taken from standard stock cultures. Half of the samples were incubated at 20°C and the rest were stored at 4°C for 120 h. Growth of microorganisms in each solution was compared by counting the number of the Colony-Forming Units (CFUs) at 0, 3, 6, 24, 72 and 120 h. Propofol supported the growth of all four microorganims at both temperatures. In contrast, thiopental and the 1:1 propofol-thiopental mixture exhibited markedly bactericidal properties on E. coli, C. albicans and P. aeruginosa and bacteriostatic effect on S. aureus.}
}