@article{MAKHILLJAVA20098111850, title = {Oral Administration of Chicken Breast Extract Activates Serotonin Metabolism in the Hippocampus of Rats}, journal = {Journal of Animal and Veterinary Advances}, volume = {8}, number = {11}, pages = {2276-2279}, year = {2009}, issn = {1680-5593}, doi = {javaa.2009.2276.2279}, url = {https://makhillpublications.co/view-article.php?issn=1680-5593&doi=javaa.2009.2276.2279}, author = {Shozo,Mikako,Yoshihisa,Fumiki and}, keywords = {Chicken breast extract,hippocampus,serotonin,5-hydroxyindoleacetic acid,rats,micro dialysis}, abstract = {We previously reported that Chicken Breast Extract (CBEX) had an antidepressant-like effect in rats. In the present study to further clarify, the mechanism of action of CBEX, the effects of CBEX on the brain serotonin (5-HT) system was investigated in the ventral hippocampus of rats, using an in vivo micro dialysis. 5-Hydroxyindoleacetic acid, a major metabolite of serotonin, was significantly increased in animals orally administered CBEX. This result indicates that CBEX may activate 5-HT metabolism in the brain. Since, a previous study indicated that orally administered CBEX increases levels of the putative neurotransmitter carnosine in the hippocampus, carnosine might be involved in the action of CBEX.} }