@article{MAKHILLJAVA20098101785, title = {Protective Effects of Nano-ZnO on the Primary Culture Mice Intestinal Epithelial Cells in in vitro Against Oxidative Injury}, journal = {Journal of Animal and Veterinary Advances}, volume = {8}, number = {10}, pages = {1964-1967}, year = {2009}, issn = {1680-5593}, doi = {javaa.2009.1964.1967}, url = {https://makhillpublications.co/view-article.php?issn=1680-5593&doi=javaa.2009.1964.1967}, author = {Wang,Ai and}, keywords = {Intestinal epithelium cell,nano-ZnO,antioxidant,antioxidant enzymes,integrity,in vitro}, abstract = {Nano-ZnO is a new products, which may used to be feed resources. The aim of this study was to exam, whether nano-ZnO is able to protect cell integrity from potential damage by free-radical oxidative injury. A 3x3 factorial experiment was used to investigate the interaction between particle diameter (15, 50 and 100 nm) and concentration (0.4, 1.6 and 6.4 μg mL-1) of the primary culture mice Intestinal Epithelium Cell (IEC) in in vitro. The results indicated that the all the nano-ZnO groups MTT OD value were significantly higher than the perhydrol group (p<0.05) and LDH decreased, but not significant (p>0.05). The MDA content in all the nano-ZnO groups were decreased significant (p<0.01). The SOD and CAT in all nano-ZnO groups were higher than the perhydrol group (p>0.05). The results shown that nano-ZnO released the IEC oxidative injury.} }